Facultad de Ciencias de la Salud




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títuloFacultad de Ciencias de la Salud
fecha de publicación26.02.2016
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Facultad de Ciencias de la Salud
JTP : Maria Alejandra Villegas Práctico Nº 3
Microcephaly
Microcephaly is a medical condition in which the circumference of the head is smaller than normal because the brain has not developed properly or has stopped growing. Microcephaly can be present at birth or it may develop in the first few years of life.

It is most often caused by genetic abnormalities that interfere with the growth of the cerebral cortex during the early months of fetal development. It is associated with Down's syndrome, chromosomal syndromes, and neurometabolic syndromes. Babies may also be born with microcephaly if, during pregnancy, their mother: abused drugs or alcohol, became infected with a cytomegalovirus, rubella,German measles, or varicella,chickenpox virus, was exposed to certain toxic chemicals, or had untreated phenylketonuria (PKU).

Babies born with microcephaly will have a smaller than normal head that will fail to grow as they progress through infancy. Depending on the severity of the accompanying syndrome, children with microcephaly may have: mental retardation, delayed motor functions and speech, facial distortions, dwarfism or short stature, hyperactivity, seizures, difficulties with coordination and balance, and other brain or neurological abnormalities.

Some children with microcephaly will have normal intelligence and a head that will grow bigger, but they will track below the normal growth curves for head circumference.

There is no treatment for microcephaly that can return a child's head to a normal size or shape. Treatment focuses on ways to decrease the impact of the associated deformities and neurological disabilities. Children with microcephaly and developmental delays are usually evaluated by a pediatric neurologist and followed by a medical management team. Early childhood intervention programs that involve physical, speech, and occupational therapists help to maximize abilities and minimize dysfunction.

Medications are often used to control seizures, hyperactivity, and neuromuscular symptoms. Genetic counseling may help families understand the risk for microcephaly in subsequent pregnancies.

Some children will only have mild disability. Others, especially if they are otherwise growing and developing normally, will have normal intelligence and continue to develop and meet regular age-appropriate milestones.

The National Institute of Neurological Disorders and Stroke (NINDS) conducts research relating to microcephaly in its laboratories at the National Institutes of Health (NIH) and supports additional research through grants to major medical institutions across the country. A small group of researchers studying a rare neurometabolic syndrome , which causes microcephaly, have successfully used amino acid replacement therapy to reduce and prevent seizures.

I.- Responda en español las siguientes preguntas según el texto.

1.- Cuándo se puede presentar la microcefalia?

2.- Cuáles pueden ser las causas de esta enfermedad?

3.- Nombre signos y síntomas de la microcefalia.-

4.- Cuál es el tratamiento para este tipo de enfermedad ?

II.- Explique en español el significado de las siguientes estrcturas.-

1.-… Babies born with microcephaly will have a smaller than normal head that will fail to grow as they progress through infancy…………………………………………….

……………………………………………………………………………………………………..

2.- Microcephaly can be present at birth……………………………………………………...

3.- It is most often caused……………………………………………………………………….

4.- Babies may also be born with microcephaly…………………………………………….

5.- …a head that will grow bigger, ………………………………………………………………

6.- There is no treatment ……………………………………….. ……………………………...

7.- Genetic counseling may help families understand the risk for microcephaly in subsequent pregnancies. ………………………………………………………………………

………………………………………………………………………………………………………..

8.- Some children will only have mild disability …………………………………………….

………………………………………………………………………………………………………..

9.-… which causes microcephaly, ………………………………………………………………

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