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BIOGRAPHICAL SKETCH

NAME

Gabriela Andrea Balogh

POSITION TITLE
Associate Professor at National Research of Council from

Argentina.

Work Place

Centro Científico Tecnológico, Bahía Blanca, Argentina.


EDUCATION/TRAINING (Begin with baccalaureate or other initial professional education, such as nursing, and include postdoctoral training.)

INSTITUTION AND LOCATION

DEGREE

(if applicable)

YEAR(s)

FIELD OF STUDY

Universidad Nacional del Sur Argentina

Universidad Nacional del Sur Argentina

Universidad Nacional Del Sur Argentina


B.S

M.S

Ph.D

1990

1994

1997

Chemist

Biochemist

Biochemistry
















  1. Positions and Honors

Positions and Employment

    1. Clinical Laboratory Assistant, Hospital of Communtiy, Pedro Luro, Argentina

    1. Urologist and Urine analysis, Hospital Penna, Bahia Blanca, Argentina

    1. Hematologist and blood clincla analysis, Hospital Penna, Bahia Blanca, Argentina

    1. Microbiologist, Hospital Penna, Bahia Blanca, Argentina

    1. Pregraduate Assistant, Universidad Nacional sel Sur, Argentina

    1. Fellow, CONICET (Natl, Research Council of Argentina), Argentina

    2. Fellow, CONICET (Natl, Research Council of Argentina), Argentina

    1. Fellow, Universidad de Santiago De Compostela, Spain

    1. Postdoctoral Fellow ,CONICET (Natl, Research Council of Argentina), Argentina

    1. Postdoctoral Associate, Fox Chase Cancer Center, PA, USA

    1. Research Associate, Fox Chase Cancer Center, PA, USA

2005-2007 Staff Scientist, Fox Chase Cancer Center, PA, USA

2007-2008 Posdoctoral Research, Department of Biochemistry, Texas A&M University, TX, USA

2008-present Associate Professor at National Research Council of Agentina, Argentina
Honors and Awards

  • 1994-1996: Fellowship for scientific research in Effect of vitamin D3 in the aging process of rat duodenum. National Council of Biochemical and technological research from Argentina Government (CONICET). Director: Dr. Anne Russo-Boland, University of South, Bahia Blanca, Buenos Aires, Argentina.

  • 1996: Fellowship to assist at the Workshop: Vesicular transport in mammalian cells. Association Biotechnological and scientific research Argentine-Brazil (CABBIO). Mendoza-Argentine.

  • 1996-1998: Fellowship for scientific research in Molecular pathway of the effect of vitamin D3 in the aging process of rat duodenum. National Council of Biochemical and Technological Research from Argentina Goverment (CONICET). Director: Dr. Anne Russo-Boland, University of South, Bahia Blanca, Buenos Aires, Argentina.

  • 1997: Fellowship to perform training course of scientist research in Laboratory of Molecular Biology from University of Santiago de Compostela, Santiago de Compostela, Spain from Feb 1997 to June 1997.

  • 1997: Fellowship to assist at the Workshop on Vitamin D from University of South, Bahía Blanca, Argentina to go to Strasburg, France, June 1997.

  • 1998-2000: Postdoctoral fellowship for scientific research in p53 protein in breast cancer patients, potential molecular marker. National Council of Biochemical and technological research from Argentina Goverment (CONICET). Director: Dr. Jose Mordoh, Fundación Federico Leloir, Buenos Aires, and IACA Laboratorios, Bahía Blanca, Argentina.

  • 2003: First Prize for the Best Movie in Oncology, from Video Primaria International Competition. Title: “GENOMIC BASES OF BREAST CARCINOGENESIS”. Director: Gabriela Balogh and Producer: Patricia Russo. Vigo, Spain, August, 2003.

  • 2006: Fellowship to assist at the Oncoconferences in Cancer Prevention from University of Saint Gallen, Saint Gallen, Switzeland, Feb 2006.

  • 2007: AACR Minority Acholar Award and participation in oral communications. American Association for Cancer Research. Los Angeles, Abril de 2007, USA.


Memberships in Professional Organizations

1. Sociedad Argentina de Investigaciones Bioquímicas SAIB (Biochemistry Research Society ), Argentine.

2. Sociedad Argentina de Farmacología Experimental SAFE (Experimental Farmacology Society), Argentine.

3. American Association of Cancer Research (AACR), Associate Member, United States, since 2001.
B. Selected Peer-Reviewed Publications (in chronological order)

  1. AGE-ASSOCIATED DECREASE IN INOSITOL 1,4,5-TRISPHOSPHATE AND DIACYLGLYCEROL GENERATION BY 1,25(OH)2-VITAMIN D3 IN RAT INTESTINE. A.R. de Boland, M.M. Facchinetti, G. Balogh, V. Massheimer and R.Boland. Cell. Signal. 8(3):153-157. (1996).

  2. INFLUENCE OF AGE ON 1,25(OH)2-VITAMIN D3 ACTIVATION OF PROTEIN KINASE C IN RAT DUODENUM. G. Balogh, R. Boland and A.R. de Boland. (Molecular and Cell Endocrinology 129: 127-133 (1997).

  3. IMPAIRMENT OF CALCITRIOL-DEPENDENT PKC PHOSPHORYLATION IN RAT INTESTINE DURING AGEING". G. Balogh, R. Boland and A.R de Boland Proceedings of The Tenth Workshop on Vitamin D Strasbourg France, A. Norman, R. Bouillon and M. Thomasset, Eds. California, USA. Pág: 379-380 (1997).

  4. “1,25-DIHYDROXY-VITAMIN D3 (CALCITRIOL)-DEPENDENT PROTEIN PHOSPHORYLATION IN RAT DUODENUM EFFECTS OF AGEING. G. Balogh, R. Boland and A.R. de Boland. Experimental Gerontology Vol. 34:983-996 (1999).

  5. EFFECT OF 1,25(OH)2-VITAMIN D3 IN THE ACTIVATION OF NATURAL KILLER CELLS: ROLE OF PROTEIN KINASE C. G. Balogh, A.R de Boland, R. Boland and P. Barja. Experimental and Mol. Pathology Vol: 67: 63-74 (1999).

  6. CULTIVO DE TRICHOMONAS VAGINALIS”. G. Niizawa, R. Costamagna y G. Balogh. AMBB Vol. 9 (1) Pág. 22-25 (1999),.

  7. 1,25(OH)2-VITAMIN D3 AFFECTS SUBCELLULAR DISTRIBUTION OF PROTEIN KINASE C ISOENZYMES IN RAT DUODENUM. G. Balogh and A.R de Boland. J. Cell. Biochem., 79 (4): 686-94 (2000).

  8. LEUKAEMIA INHIBITORY FACTOR OR ONCOSTATIN M (OSM) INDUCE DNA SYNTHESIS IN SWISS MOUSE 3T3 CELLS VIA SIGNALLING MECHANISMS DISPLAYING A REDUCER INVOLVEMENT OF p42-MAPK ACTIVITY. M. Sauane, F. Rogers, G. Balogh. O. Pignataro, P. Rudland and L. Jimenez de Asúa.
  9. DEFECTIVE MISMATCH REPAIR PROTEIN PMS2 IS INVOLVED IN HUMAN BREAST CANCER”. Gabriela A. Balogh, Irma H. Russo, and Jose Russo. Int. J. of Oncology 23:411-419 (2003).


  10. ESTROGEN AND ITS METABOLITES ARE CARCINOGENIC AGENTS IN HUMAN BREAST EPITHELIAL CELLS. J. Russo, M. H. Lareef, G. Balogh, S. Guo and I. H. Russo. J. of Steroid Biochem and Mol. Biol. 87:1-25 (2003).

  11. EVIDENCE FOR THE NOTCH SIGNALING PATHWAY ON THE ROLE OF ESTROGEN IN AGIOGENESIS. Soares, R. Balogh, G., Guo, S., Gärtner F. Russo J. Schmitt F. Mol. Endocrinology Jun 10 [Epub ahead of print] (2004).

  12. DEFECTIVE MISMATCH REPAIR PROTEIN PMS2 IS INVOLVED IN THE NEOPLASTIC TRANSFORMATION OF HUMAN BREAST EPITHELIAL CELLS. G. A Balogh, I.H. Russo and J. Russo. Int. J. of Oncology 2:381-7 (2004).

  13. COMPARATIVE GENOMIC HYBRIDIZATION AND CHROMOSOME ABERRATIONS DURING BREAST CANCER INITIATION AND PROGRESSION. Gabriela A. Balogh*, Binaifer R. Balsara, Joseph Testa, Irma H. Russo and Jose Russo, Genes Chromosomes and Cancer (2004).

  14. The role of pregnancy in breast cancer. Jose Russo, Raquel Moral, Gabriela Balogh, Daniel Mailo, Rebeca Heulings, Patricia A. Russo, and Irma H. Russo. Breast Cancer Research, 7:131-142, (2005).

  15. BREAST DIFFERENTIATION AND ITS IMPLICATION IN CANCER PREVENTION. J. Russo, D. Mailo, YF Hu, G. Balogh, F. Sheriff and I. Russo. Clinical Can. Res. Vol 11:1-6 (2005).

  16. IDENTIFICATION OF CRIPTO-1 AS A NOVEL SEROLOGICAL MARKER FOR CANCER. C. Bianco, L.Strizzi, M. Mancino, A. Rehman, S. Hamada, K. Watanabe, A. De Luca, B. Jones, G.Balogh, J. Russo, D. Mailo, R. Palaia, G. D’Aiuto, G. Botti, D. S. Salomon and N. Normano. Submitted to , December (2005).

  17. The concept of Stem cell in the Mammary GLand and ist implication in morphogenesis, cancer and prevention. Russo J., Balogh GA, Chen J; Fernandez SV, Liu M; Mailo D. ;Moral R.; Sheriff F, Vanegas JE, Wang R, and Russo IH. Frontiers of Cancer, 11: 151-162, (2005).

  18. MOLECULAR BASIS OF PREGNANCY INDUCED BREAST CANCER PROTECTION. Jose Russo, Gabriela A Balogh, Rebecca Heulings, Daniel A. Mailo, Raquel Moral, Patricia A. Russo, Fathima Sheriff, Johana Vanegas and Irma H. Russo. European Journal of Cancer Prevention, review (2005).

  19. HUMAN CHORIONIC GONADOTROPIN (HCG) INDUCES SPECIFIC MOLECULAR PATHWAY OF CELL DIFFERENTIATION IN THE MAMMARY GLAND OF MACACA FASCICULARIS D. Mailo, P.A. Russo, G. A. Balogh, I. H. Russo, F. Sheriff, S.A Appt, R.M. Blair, K.M.Cline, T.B. Clarkson and J. Russo.. European J. of Cancer Vol 4 (1):49, (2006).

  20. IMMUNE SURVEILLANCE RELATED GENES ARE SIGNIFICANTLY OVER EXPRESSED IN THE POSTMENOPAUSAL BREAST EPITHELIA OF PAROUS WOMEN. Balogh, G. A., Russo, I.H., Spittle C., Heulings R.C, Mailo, D.A. and Russo.. European J. of Cancer, Vol 4 (1):45 (2006).

  21. MUTANT P53 PROTEIN IN SERUM COULD BE USED AS A MOLECULAR MARKER IN HUMAN BREAST CANCER. Balogh, G.A; Corte, M.M; Nardi, H; Vincent, Eduardo; Martínez, D; Cafasso, M.E; Frizza, A;Ponce, G, Vincent, Esteban; Barutta, E; Lizarraga, P; Lizarraga, G3,4; Roncoroni, P; Monti, C; Paolillo, E; Vincent, R; Quatroquio, R; Grimi, C; Maturi, H; Aimale, M; Spinsanti, C; Montero, H; Santiago, J; Schulman, L; Rivadulla, M; Machiavelli, M; Salum, G; Cuevas, M.A; Piccolini, J; Gentili, A; Gentili, R and Mordoh, J.. Int. J. of Oncology , Apr, 28 (4):995-1002, (2006).

  22. GENOMIC CHANGES INDUCED IN THE MAMMARY GLAND OF RATS EXPOSED NEONATALLY AND PREPUBERTALLY TO BISPHENOL A AND BUTYL BEZYL PHTHALATE. Moral, R; Wang, R. Balogh, G.A; Mailo, D; Russo, I.H; Lamartiniere, C and Russo, J.. BMC Molecular Biology, 2007 6;8:453.

  23. DETECTION OF CHROMOSOMAL ABERRATIONS BY COMPARATIVE GENOMIC HYBRIDIZATION DURING TRANSFORMATION OF HUMAN BREAST EPITHELIAL CELLS IN VITRO. Balogh, G.A; Russo, I.H; Balsara, B.R and Russo, J.. Int. Journal of Oncology, 2006;29(4):877-81.

  24. THE MISMATCH REPAIR HPMS2 IS MUTATED IN PRIMARY BREAST CANCER. Balogh, G.A; Heulings, R.C and Russo, J.. Int. J. of Molecular Medicine, 2006 Nov;18(5):853-7.

  25. IDENTIFICATION OF CRIPTO-1 AS A NOVEL SEROLOGIC MARKER FOR BREAST AND COLON CANCER. Bianco, C;Strizzi, L; Mancino, M; Rehman, A; Hamada, S; Watanabe, K; De Luca, A; Jones, B, Balogh, G; Russo, J; Mailo, D; Palaia, R; D’Aiuto, G; Botti, G; Salomon D. and Normanno, N.. Clin Cancer Res. 2006 Sep 1;12(17):5158-64

  26. METHODOLOGICAL APPROACH TO STUDY THE GENOMIC PROFILE OF THE HUMAN BREAST. Balogh GA, Heulings R, Mailo D, Wang R, Li YS, Hardy R, Russo J. Int J Oncol. 2007 Aug;31(2):253-60.

  27. IMMUNE-SURVEILLANCE AND PROGRAMMED CELL DEATH-RELATED GENES ARE SIGNIFICANTLY OVEREXPRESSED IN THE NORMAL BREAST EPITHELIUM OF POSTMENOPAUSAL PAROUS WOMEN. Balogh GA, Russo IH, Spittle C, Heulings R, Russo J. Int J Oncol. 2007 Aug;31(2):303-12.

  28. THE GENOMIC SIGNATURE OF BREAST CANCER PREVENTION. Russo J, Balogh G, Mailo D, Russo PA, Heulings R, Russo IH. Recent Results Cancer Res. 2007;174:131-50. Review.

  29. THE BREAST OF PAROUS WOMEN WITHOUT CANCER HAS A DIFFERENT GENOMIC PROFILE COMPARED TO THOSE WITH CANCER. Balogh GA, Russo J, Mailo DA, Heulings R, Russo PA, Morrison P, Sheriff F, Russo IH. Int J Oncol. 2007 Nov;31(5):1165-75.

  30. BREAST CANCER PREVENTION. Russo, I.H, Balogh, G; Russo J.. Climacteric. 2007 Oct;10 Suppl 2:47-53.

  31. FULL-TERM PREGNANCY INDUCES A SPECIFIC GENOMIC SIGNATURE IN THE HUMAN BREAST. Russo, I.H, Balogh, G; Russo J. Cancer Epidemiol Biomarkers Prev. 2008 Jan;17(1):51-66.

  32. SEROLOGICAL LEVELS OF MUTATED P53 PROTEIN ARE HIGHLY DETECTED AT EARLY STAGES IN BREAST CANCER PATIENTS. G. A. Balogh, D. Mailo, H. Nardi, M. M. Corte, E. Vincent, E. Barutta, G. Lizarraga, P. Lizarraga, H. Montero, R.Gentili.. Experimental and Therapeutic Medicine, Volume 1 Number 2, March-April 2010.

  33. ROLE OF HER2 EXPRESSION IN NON-PALPABLE BREAST CANCER PATIENTS. Domínguez W, Nardi H, Lizarraga G, Montero H, Vincent E, Gentili A and Balogh G. Experimental and Therapeutic Medicine, Volume 1 Number 4: 597-602, July-August 2010.

  34. HONGOS COMESTIBLES Y MEDICINALES. Ramiro González Matute, Débora Figlas, Pablo Postemsky, Gabriela Balogh y Néstor Curvetto. Revista Ciencia Hoy.. Diciembre 2010. Vol 20 (120): 9-15

  35. APOPTOSIS AND CELL-DEATH INDUCTION IN BREAST CANCER EPITHELIAL CELLS INDUCED BY BETA GLUCANS COMPOUND. Soares R, Joos G, Obiol D, Alonso E and Balogh G. Journal of Medicinal Food, April, 2011 Vol 20(2): 1-10.

  36. GENOMIC SIGNATURE INDUCES BY MAITAKE D-FRACTION IN BREAST CANCER CELLS. Alonso E, Ferronato MJ, Orozco M, Nieto A and Balogh G. Manuscript in preparation.


C. Books Chapters publications
1. THE GENOMIC SIGNATURE OF BREAST CANCER PREVENTION. Russo J, Balogh G, Mailo D, Russo P, Heulings R and Russo I. Chapter 12. Pages: 133-160. Book: Recent Results in Cancer Research Vol 174. Spring-Verlang Berlin Heidelberg, 2007.

2. DIAGNOSTICO PRECOZ DE CÁNCER DE MAMA POR ANÁLISIS GENÓMICO EN CÉLULAS EPITELIALES OBTENIDAS POR ASPIRADO MAMARIO. Russo Jose and Balogh Gabriela. Chapter 3.1 Pages: 92-114. Book: Cancer de mama. Segunda Edicion. Ed. McGraw Hill. Venezuela, 2007.

3. THE ROLE OF ESTROGEN IN BREAST CANCER. Balogh G, Russo J, Hassan L and Russo I. Chapter 4. Book: Molecular Basis of Breast Cancer Prevention and Treatment. Ed. Springer, Berlin Heidelberg, 2005.
C. Important Conferences Given

    1. Age-Related Impairment of 1,25-(OH)2-Vitamin D3 Activation of Protein Kinase C In Rat Duodenum. Gabriela Balogh, A.R. De Boland and R. Boland. Mendoza, Noviembre, 1996, Argentine.

    2. Efectos del 1,25(OH)2-Vitamina D3 sobre el envejecimiento celular en duodeno de rata. Defense of Tesis Doctoral in Biochemistry. Gabriela Balogh, June, 23th, 1998, Bahia Blanca, Argentine.

    3. p53 Mutant Protein In Serum Could Be Used As A Breast Cancer Marker. IACA Instituto de Analistas Clínicos Asociados. Gabriela Balogh. Noviembre, 1999, Bahía Blanca, Argentine.

    4. P53 Mutant Protein in Serum as a Breast Cancer Marker. IACA Instituto de Analistas Clinicos Asociados. Gabriela Balogh. August, 2000, Bahia Blanca, Argentine.

    5. Comparative Study of Rat Oligonucleotide Microarray. Gabriela Balogh, Ph.D, Richard Wang, M.D, Ph.D. and Jose Russo, M.D. Abril 27th, 2004. Fox Chase Cancer Center.Philadelphia, PA, USA.

    6. Ductal Lavage and Breast Cancer Early Diagnosis. IACA Laboratorios, Buenos Aires, Argentina. Gabriela Balogh, July, 2004.

    7. Análisis cito-genomicos de celulas de fluido mamario: Nuevos metodos de diagnostico precoz para cancer de mama. Tijuana, Mexico. Sociedad de Ginecología de Tijuana. Tijuana, Mexico. Gabriela Balogh, September 2004.

    8. Genomic Signature induced by Pregnancy in human breast. Christiana Health Hospital. Delaware, USA. Gabriela Balogh April, 6th, 2005.

    9. Genomic Expression of BBP and BPA in rat mammary gland. University of Cincinatti, Oregon, USA. Gabriela Balogh May, 2005.

    10. Genomic Signature induced by Pregnancy in human breast, Part II. Christiana Health Hospital. Delaware, USA. Gabriela Balogh October, 5th, 2005.

    11. Immune surveillance related genes are significantly over expressed in the postmenopausal breast epithelia of parous women. University of Saint Gallen, Medical School, Saint Gallen, Switzeland, Gabriela Balogh Feb, 16th, 2006.

    12. El método de Ductal Lavage. Conference organized by LatinaShare Corporation, New York City, USA, Gabriela Balogh, May, 23th, 2006.

    13. Identification of a unique genomic signature induced by early pregnancy in the human breast of postmenopausal women. Gabriela Balogh, Daniel Mailo, Rebecca Heulings, Patricia Russo, Peter Morrison, Irma Russo, Fathima Sheriff and Jose Russo. American Association for Cancer Research. Minority Scholar Award. Los Angeles, CA, USA, April 2007.

    14. Bases genómicas de la Carcinogenesis Mamaria. Depto. Biotechnology. Gabriela Balogh. Centro Cientifico Tecnológico Bahia Blanca, CERZOS-CONICET, Bahia Blanca-Argentina. September 2007.

    15. Pruebas genéticas para determinar paternidad. Programa Más Vale de Mónica Nicosia, Canal 2 de Cable Canal de BBC. Gabriela Balogh. Bahía Blanca, Argentina. December 2007.

    16. Cáncer de mama y nuevos métodos para determinar riesgo elevado en pacientes con antecedentes familiares de cáncer. Gabriela Balogh. Programa matutino de radiodifusión, Radio 10 de Pedro Luro. Conexión telefónica directa al programa de Radio 10, Noviembre de 2008.

    17. Cáncer de mama y nuevos métodos para determinar riesgo elevado en pacientes con antecedentes familiares de cáncer. Gabriela Balogh. Conferencia en el Centro Integral de Diagnóstico (CID) de la Lic. Leticia Balogh de Navone en Pedro Luro, Pcia. Buenos Aires, Argentina, November 2008.

    18. Día Internacional del Cáncer de mama. Notas Públicas de la Revista de CERZOS. Gabriela Balogh. CERZOS-CONICET, Bahía Blanca, Argentina. December 2008.

    19. “Potential effects of Medicinal Mushrooms in breast cancer. Potenciales efectos terapéuticos de hongos medicinales en cáncer de mama. Dra. Gabriela A. Balogh. Lab. Hongos Comestibles y Medicinales-CERZOS- Centro Científico Tecnológico CONICET. FISA 2009, Bahía Blanca, Argentina. April 2009.

    20. “Beta Glucans applications in breast cancer. Aplicación de beta glucanos en cancer de mama. Dra. Gabriela Balogh. Conference to medical doctors and oncologists. Auditórium, CERZOS- Centro Científico Tecnológico CONICET. May 6th, 2009.

    21. “Integrative Medicine”: Maitake as an example of natural product with anti-tumoral action”. Dra. Gabriela A. Balogh, Bahía Blanca. Universidad Nacional del Sur. Bahía Blanca, Argentina, October 2nd 2009.

    22. Aplication of Maitake to breast cancer patients. Dra. Gabriela A. Balogh. Congreso FUNGI 2009. 11th November 2009 Buenos Aires, Argentina.

    23. ROLE OF BETA GLUCAN IN THE EFECTIVENESS TO PREVENT BREAST TUMORIGENESIS BY ACTIVATION OF HOST IMMUNOSURVEILLANCE MECHANISMS. Dr. Gabriela A. Balogh. 3rd World Cancer Congress 2010-Breast Cancer Conference, Shanghai-China, 10-12 April 2010.

    24. Role of Medicinal Mushrooms in breast cancer. Dr. Gabriela Balogh. Curso de Postgrado: Hongos Comestibles y Medicinales, CERZOS-CONICET. December 2010, Bahía Blanca, Argentina.

    25. Integrative Oncology and Scientific Protocols demonstrate the effect of complementary therapies in breast cancer patients. Dr. Gabriela Balogh. I Integrative Oncology International Meeting, June 24-25, 2011, Buenos Aires, Argentina.

    26. Molecular Bases of Breast carcinogenesis. Postgraduates course to medical doctors. Dr. Gabriela Balogh. Department of Gynecology, Sao Paulo University, Hospital das Clinicas, 28th June -15th July, 2011, Riberao Preto, Brasil.




PHS 398/2590 (Rev. 09/04) Page Balogh, Gabriela Andrea. Biographical Sketch

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